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Towards a Synthesis of the Non-Genetic and Genetic Views of Cancer in Understanding Pancreatic Ductal Adenocarcinoma Initiation and Prevention

SIMPLE SUMMARY: Cancer initiation and progression has been studied in purely genetic terms for decades. Implicit in this view is that all cells in a tissue are phenotypically identical until a single cell acquires a set of mutations that will eventually lead to malignancy. This model does not fully...

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Detalles Bibliográficos
Autores principales: Gopalan, Vishaka, Hannenhalli, Sridhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093726/
https://www.ncbi.nlm.nih.gov/pubmed/37046820
http://dx.doi.org/10.3390/cancers15072159