Palmitate-Induced Cardiac Lipotoxicity Is Relieved by the Redox-Active Motif of SELENOT through Improving Mitochondrial Function and Regulating Metabolic State

Cardiac lipotoxicity is an important contributor to cardiovascular complications during obesity. Given the fundamental role of the endoplasmic reticulum (ER)-resident Selenoprotein T (SELENOT) for cardiomyocyte differentiation and protection and for the regulation of glucose metabolism, we took adva...

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Detalles Bibliográficos
Autores principales: Rocca, Carmine, De Bartolo, Anna, Guzzi, Rita, Crocco, Maria Caterina, Rago, Vittoria, Romeo, Naomi, Perrotta, Ida, De Francesco, Ernestina Marianna, Muoio, Maria Grazia, Granieri, Maria Concetta, Pasqua, Teresa, Mazza, Rosa, Boukhzar, Loubna, Lefranc, Benjamin, Leprince, Jérôme, Gallo Cantafio, Maria Eugenia, Soda, Teresa, Amodio, Nicola, Anouar, Youssef, Angelone, Tommaso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093731/
https://www.ncbi.nlm.nih.gov/pubmed/37048116
http://dx.doi.org/10.3390/cells12071042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093731/
https://www.ncbi.nlm.nih.gov/pubmed/37048116
http://dx.doi.org/10.3390/cells12071042

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