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Palmitate-Induced Cardiac Lipotoxicity Is Relieved by the Redox-Active Motif of SELENOT through Improving Mitochondrial Function and Regulating Metabolic State
Cardiac lipotoxicity is an important contributor to cardiovascular complications during obesity. Given the fundamental role of the endoplasmic reticulum (ER)-resident Selenoprotein T (SELENOT) for cardiomyocyte differentiation and protection and for the regulation of glucose metabolism, we took adva...
Autores principales: | Rocca, Carmine, De Bartolo, Anna, Guzzi, Rita, Crocco, Maria Caterina, Rago, Vittoria, Romeo, Naomi, Perrotta, Ida, De Francesco, Ernestina Marianna, Muoio, Maria Grazia, Granieri, Maria Concetta, Pasqua, Teresa, Mazza, Rosa, Boukhzar, Loubna, Lefranc, Benjamin, Leprince, Jérôme, Gallo Cantafio, Maria Eugenia, Soda, Teresa, Amodio, Nicola, Anouar, Youssef, Angelone, Tommaso |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093731/ https://www.ncbi.nlm.nih.gov/pubmed/37048116 http://dx.doi.org/10.3390/cells12071042 |
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