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R-Loops at Chromosome Ends: From Formation, Regulation, and Cellular Consequence

SIMPLE SUMMARY: R-loops, also referred to as RNA: DNA hybrids, are tripartite structures formed when a single-stranded RNA molecule forms a complex with a double-stranded DNA duplex via homology-directed base pairing. Many cellular functions are thought to be mediated by R-loops, including gene regu...

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Detalles Bibliográficos
Autores principales: Gong, Yi, Liu, Yie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093737/
https://www.ncbi.nlm.nih.gov/pubmed/37046839
http://dx.doi.org/10.3390/cancers15072178