Accurate Prediction of Transcriptional Activity of Single Missense Variants in HIV Tat with Deep Learning

Tat is an essential gene for increasing the transcription of all HIV genes, and affects HIV replication, HIV exit from latency, and AIDS progression. The Tat gene frequently mutates in vivo and produces variants with diverse activities, contributing to HIV viral heterogeneity as well as drug-resista...

Descripción completa

Detalles Bibliográficos
Autores principales: Derbel, Houssemeddine, Giacoletto, Christopher J., Benjamin, Ronald, Chen, Gordon, Schiller, Martin R., Liu, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093788/
https://www.ncbi.nlm.nih.gov/pubmed/37047108
http://dx.doi.org/10.3390/ijms24076138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093788/
https://www.ncbi.nlm.nih.gov/pubmed/37047108
http://dx.doi.org/10.3390/ijms24076138

Ejemplares similares