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Melanoma Cells Produce Large Vesicular-Bodies That Cause Rapid Disruption of Brain Endothelial Barrier-Integrity and Disassembly of Junctional Proteins

It is known that many cells produce extracellular vesicles, and this includes a range of different cancer cell types. Here we demonstrate the profound effects of large vesicular-like bodies produced by melanoma cells on the barrier integrity of human brain endothelial cells. These vesicular-bodies h...

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Detalles Bibliográficos
Autores principales: Spurling, Dayna, Anchan, Akshata, Hucklesby, James, Finlay, Graeme, Angel, Catherine E., Graham, E. Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093843/
https://www.ncbi.nlm.nih.gov/pubmed/37047054
http://dx.doi.org/10.3390/ijms24076082