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Melanoma Cells Produce Large Vesicular-Bodies That Cause Rapid Disruption of Brain Endothelial Barrier-Integrity and Disassembly of Junctional Proteins
It is known that many cells produce extracellular vesicles, and this includes a range of different cancer cell types. Here we demonstrate the profound effects of large vesicular-like bodies produced by melanoma cells on the barrier integrity of human brain endothelial cells. These vesicular-bodies h...
Autores principales: | Spurling, Dayna, Anchan, Akshata, Hucklesby, James, Finlay, Graeme, Angel, Catherine E., Graham, E. Scott |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093843/ https://www.ncbi.nlm.nih.gov/pubmed/37047054 http://dx.doi.org/10.3390/ijms24076082 |
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