Sigma-2 Receptors—From Basic Biology to Therapeutic Target: A Focus on Age-Related Degenerative Diseases

There is a large unmet medical need to develop disease-modifying treatment options for individuals with age-related degenerative diseases of the central nervous system. The sigma-2 receptor (S2R), encoded by TMEM97, is expressed in brain and retinal cells, and regulates cell functions via its co-rec...

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Detalles Bibliográficos
Autores principales: Lizama, Britney N., Kahle, Jennifer, Catalano, Susan M., Caggiano, Anthony O., Grundman, Michael, Hamby, Mary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093856/
https://www.ncbi.nlm.nih.gov/pubmed/37047224
http://dx.doi.org/10.3390/ijms24076251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093856/
https://www.ncbi.nlm.nih.gov/pubmed/37047224
http://dx.doi.org/10.3390/ijms24076251

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