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Sigma-2 Receptors—From Basic Biology to Therapeutic Target: A Focus on Age-Related Degenerative Diseases
There is a large unmet medical need to develop disease-modifying treatment options for individuals with age-related degenerative diseases of the central nervous system. The sigma-2 receptor (S2R), encoded by TMEM97, is expressed in brain and retinal cells, and regulates cell functions via its co-rec...
Autores principales: | Lizama, Britney N., Kahle, Jennifer, Catalano, Susan M., Caggiano, Anthony O., Grundman, Michael, Hamby, Mary E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093856/ https://www.ncbi.nlm.nih.gov/pubmed/37047224 http://dx.doi.org/10.3390/ijms24076251 |
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