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ABCB1 and ABCC1 Function during TGF-β-Induced Epithelial-Mesenchymal Transition: Relationship between Multidrug Resistance and Tumor Progression

Multidrug resistance (MDR) and induction of metastasis are some of the puzzles encountered during cancer chemotherapy. The MDR phenotype is associated with overexpression of ABC transporters, involved in drug efflux. Metastasis originates from the epithelial-mesenchymal transition (EMT), in which ce...

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Detalles Bibliográficos
Autores principales: da Costa, Kelli Monteiro, Freire-de-Lima, Leonardo, da Fonseca, Leonardo Marques, Previato, José Osvaldo, Mendonça-Previato, Lucia, Valente, Raphael do Carmo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10093952/
https://www.ncbi.nlm.nih.gov/pubmed/37047018
http://dx.doi.org/10.3390/ijms24076046