Iron Limitation Restores Autophagy and Increases Lifespan in the Yeast Model of Niemann–Pick Type C1

Niemann–Pick type C1 (NPC1) is an endolysosomal transmembrane protein involved in the export of cholesterol and sphingolipids to other cellular compartments such as the endoplasmic reticulum and plasma membrane. NPC1 loss of function is the major cause of NPC disease, a rare lysosomal storage disord...

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Detalles Bibliográficos
Autores principales: Martins, Telma S., Costa, Rafaela S., Vilaça, Rita, Lemos, Carolina, Teixeira, Vitor, Pereira, Clara, Costa, Vítor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094029/
https://www.ncbi.nlm.nih.gov/pubmed/37047194
http://dx.doi.org/10.3390/ijms24076221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094029/
https://www.ncbi.nlm.nih.gov/pubmed/37047194
http://dx.doi.org/10.3390/ijms24076221

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