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iE-DAP Induced Inflammatory Response and Tight Junction Disruption in Bovine Mammary Epithelial Cells via NOD1-Dependent NF-κB and MLCK Signaling Pathway

γ-D-glutamyl-meso-diaminopimelic acid (iE-DAP), a bacterial cell wall component, can trigger an inflammatory response. A mammary inflammatory response causes tight junction (TJ) dysfunction. This study aimed to explore the effects and involved mechanisms of iE-DAP-induced inflammatory response on th...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Li, Xuerui, Han, Zhengqiang, Meng, Meijuan, Shi, Xiaoli, Wang, Lairong, Chen, Mengru, Chang, Guangjun, Shen, Xiangzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094069/
https://www.ncbi.nlm.nih.gov/pubmed/37047240
http://dx.doi.org/10.3390/ijms24076263