Discovery of a photoactivatable dimerized STING agonist based on the benzo[b]selenophene scaffold

Stimulator of interferon genes (STING) agonism presents a powerful weapon for cancer immunotherapy. This study reports a novel dimerized STING agonist diBSP01, which exhibited promising STING binding and activation properties in vitro, based on the benzo[b]selenophene scaffold. Meanwhile, shielding...

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Detalles Bibliográficos
Autores principales: Liu, Dongyu, Yu, Bin, Guan, Xin, Song, Bin, Pan, Huikai, Wang, Renbing, Feng, Xi, Pan, Lixia, Huang, Huidan, Wang, Zhe, Wu, Hongxi, Qiu, Zhixia, Li, Zhiyu, Bian, Jinlei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094158/
https://www.ncbi.nlm.nih.gov/pubmed/37063808
http://dx.doi.org/10.1039/d2sc06860e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094158/
https://www.ncbi.nlm.nih.gov/pubmed/37063808
http://dx.doi.org/10.1039/d2sc06860e

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