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Development of Novel Pt(IV)-Carbohydrate Derivatives as Targeted Anticancer Agents against Osteosarcoma

Despite the enormous importance of cisplatin as a chemotherapeutic agent, its application is impacted by dose-limiting side effects and lack of selectivity for cancer cells. Researchers can overcome these issues by taking advantage of the pro-drug nature of the platinum(IV) oxidation state, and by m...

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Detalles Bibliográficos
Autores principales: Moynihan, Eoin, Panseri, Silvia, Bassi, Giada, Rossi, Arianna, Campodoni, Elisabetta, Dempsey, Eithne, Montesi, Monica, Velasco-Torrijos, Trinidad, Montagner, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094171/
https://www.ncbi.nlm.nih.gov/pubmed/37047001
http://dx.doi.org/10.3390/ijms24076028