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Role of Macrophages in Sickle Cell Disease Erythrophagocytosis and Erythropoiesis

Sickle cell disease (SCD) is an inherited blood disorder caused by a β-globin gene point mutation that results in the production of sickle hemoglobin that polymerizes upon deoxygenation, causing the sickling of red blood cells (RBCs). RBC deformation initiates a sequence of events leading to multipl...

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Detalles Bibliográficos
Autores principales: Sesti-Costa, Renata, Costa, Fernando F., Conran, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094208/
https://www.ncbi.nlm.nih.gov/pubmed/37047304
http://dx.doi.org/10.3390/ijms24076333