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Antiproliferative Mechanisms of a Polyphenolic Combination of Kaempferol and Fisetin in Triple-Negative Breast Cancer Cells

Herein, we investigate the combinatorial therapeutic effects of naturally occurring flavonoids kaempferol (K) and fisetin (F) on triple-negative breast cancer (TNBC: MDA-MB-231 cell line). Dose-dependent MTT assay results show that K and F exhibited cytotoxicity in MDA-MB-231 cells at 62 and 75 μM (...

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Detalles Bibliográficos
Autores principales: Afzal, Mohd., Alarifi, Abdullah, Karami, Abdalnaser Mahmoud, Ayub, Rashid, Abduh, Naaser A. Y., Saeed, Waseem Sharaf, Muddassir, Mohd.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094218/
https://www.ncbi.nlm.nih.gov/pubmed/37047366
http://dx.doi.org/10.3390/ijms24076393