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Mouse Models with SGLT2 Mutations: Toward Understanding the Role of SGLT2 beyond Glucose Reabsorption

The sodium–glucose cotransporter 2 (SGLT2) mainly carries out glucose reabsorption in the kidney. Familial renal glycosuria, which is a mutation of SGLT2, is known to excrete glucose in the urine, but blood glucose levels are almost normal. Therefore, SGLT2 inhibitors are attracting attention as a n...

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Detalles Bibliográficos
Autores principales: Unno, Keiko, Taguchi, Kyoko, Takagi, Yoshiichi, Hase, Tadashi, Meguro, Shinichi, Nakamura, Yoriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094282/
https://www.ncbi.nlm.nih.gov/pubmed/37047250
http://dx.doi.org/10.3390/ijms24076278