Mn(III) Porphyrin, MnTnBuOE-2-PyP(5+), Commonly Known as a Mimic of Superoxide Dismutase Enzyme, Protects Cardiomyocytes from Hypoxia/Reoxygenation Induced Injury via Reducing Oxidative Stress

Myocardial ischemia-reperfusion injury (I/R) causes damage to cardiomyocytes through oxidative stress and apoptosis. We investigated the cardioprotective effects of MnTnBuOE-2-PyP(5+) (BMX-001), a superoxide dismutase mimic, in an in vitro model of I/R injury in H9c2 cardiomyocytes. We found that BM...

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Detalles Bibliográficos
Autores principales: Sharma, Sudha, Sharma, Papori, Subedi, Utsab, Bhattarai, Susmita, Miller, Chloe, Manikandan, Shrivats, Batinic-Haberle, Ines, Spasojevic, Ivan, Sun, Hong, Panchatcharam, Manikandan, Miriyala, Sumitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094288/
https://www.ncbi.nlm.nih.gov/pubmed/37047131
http://dx.doi.org/10.3390/ijms24076159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094288/
https://www.ncbi.nlm.nih.gov/pubmed/37047131
http://dx.doi.org/10.3390/ijms24076159

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