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Mn(III) Porphyrin, MnTnBuOE-2-PyP(5+), Commonly Known as a Mimic of Superoxide Dismutase Enzyme, Protects Cardiomyocytes from Hypoxia/Reoxygenation Induced Injury via Reducing Oxidative Stress
Myocardial ischemia-reperfusion injury (I/R) causes damage to cardiomyocytes through oxidative stress and apoptosis. We investigated the cardioprotective effects of MnTnBuOE-2-PyP(5+) (BMX-001), a superoxide dismutase mimic, in an in vitro model of I/R injury in H9c2 cardiomyocytes. We found that BM...
Autores principales: | Sharma, Sudha, Sharma, Papori, Subedi, Utsab, Bhattarai, Susmita, Miller, Chloe, Manikandan, Shrivats, Batinic-Haberle, Ines, Spasojevic, Ivan, Sun, Hong, Panchatcharam, Manikandan, Miriyala, Sumitra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094288/ https://www.ncbi.nlm.nih.gov/pubmed/37047131 http://dx.doi.org/10.3390/ijms24076159 |
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