Deciphering the Polyglucosan Accumulation Present in Lafora Disease Using an Astrocytic Cellular Model

Lafora disease (LD) is a neurological disorder characterized by progressive myoclonus epilepsy. The hallmark of the disease is the presence of insoluble forms of glycogen (polyglucosan bodies, or PGBs) in the brain. The accumulation of PGBs is causative of the pathophysiological features of LD. Howe...

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Detalles Bibliográficos
Autores principales: Moreno-Estellés, Mireia, Campos-Rodríguez, Ángela, Rubio-Villena, Carla, Kumarasinghe, Lorena, Garcia-Gimeno, Maria Adelaida, Sanz, Pascual
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094345/
https://www.ncbi.nlm.nih.gov/pubmed/37046993
http://dx.doi.org/10.3390/ijms24076020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094345/
https://www.ncbi.nlm.nih.gov/pubmed/37046993
http://dx.doi.org/10.3390/ijms24076020

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