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VEGF Induces Expression of Genes That Either Promote or Limit Relaxation of the Retinal Endothelial Barrier

The purpose of this study was to identify genes that mediate VEGF-induced permeability. We performed RNA-Seq analysis on primary human retinal endothelial cells (HRECs) cultured in normal (5 mM) and high glucose (30 mM) conditions that were treated with vehicle, VEGF, or VEGF then anti-VEGF. We filt...

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Detalles Bibliográficos
Autores principales: McCann, Maximilian, Li, Yueru, Baccouche, Basma, Kazlauskas, Andrius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094353/
https://www.ncbi.nlm.nih.gov/pubmed/37047375
http://dx.doi.org/10.3390/ijms24076402