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Double FIT hybridization probes – towards enhancing brightness, turn-on and specificity of RNA detection

Efficient fluorogenic hybridization probes combine high brightness and specificity of fluorescence signaling with large turn-on of fluorescence. Herein, we present an approach to enhance signaling by combining two identical fluorescence base surrogates in FIT(2) probes. Provided there is a suitable...

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Detalles Bibliográficos
Autores principales: Schöllkopf, Sophie, Knoll, Andrea, Homer, Amal, Seitz, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094420/
https://www.ncbi.nlm.nih.gov/pubmed/37063796
http://dx.doi.org/10.1039/d3sc00363a

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