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Novel Activity of ODZ10117, a STAT3 Inhibitor, for Regulation of NLRP3 Inflammasome Activation

The NLRP3 inflammasome serves as a host defense mechanism against various pathogens, but there is growing evidence linking its activation in sterile condition to diverse inflammatory diseases. Therefore, the identification of specific inhibitors that target NLRP3 inflammasome activation is meaningfu...

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Detalles Bibliográficos
Autores principales: Kang, Ju-Hui, Lee, Se-Bin, Seok, Jiu, Kim, Dong-Hyuk, Ma, Gaeun, Park, Jooho, Jeong, Ae Jin, Ye, Sang-Kyu, Kang, Tae-Bong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094431/
https://www.ncbi.nlm.nih.gov/pubmed/37047051
http://dx.doi.org/10.3390/ijms24076079