Methylene Blue Induces Antioxidant Defense and Reparation of Mitochondrial DNA in a Nrf2-Dependent Manner during Cisplatin-Induced Renal Toxicity

Cisplatin is a platinum-based cytostatic drug that is widely used for cancer treatment. Mitochondria and mtDNA are important targets for platinum-based cytostatics, which mediates its nephrotoxicity. It is important to develop therapeutic approaches to protect the kidneys from cisplatin during chemo...

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Detalles Bibliográficos
Autores principales: Samoylova, Natalia A., Gureev, Artem P., Popov, Vasily N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094522/
https://www.ncbi.nlm.nih.gov/pubmed/37047089
http://dx.doi.org/10.3390/ijms24076118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094522/
https://www.ncbi.nlm.nih.gov/pubmed/37047089
http://dx.doi.org/10.3390/ijms24076118

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