The Role of LFA-1 for the Differentiation and Function of Regulatory T Cells—Lessons Learned from Different Transgenic Mouse Models

Regulatory T cells (Treg) are essential for the maintenance of peripheral tolerance. Treg dysfunction results in diverse inflammatory and autoimmune diseases with life-threatening consequences. β(2)-integrins (CD11a-d/CD18) play important roles in the migration of leukocytes into inflamed tissues an...

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Detalles Bibliográficos
Autores principales: Klaus, Tanja, Wilson, Alicia, Fichter, Michael, Bros, Matthias, Bopp, Tobias, Grabbe, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094578/
https://www.ncbi.nlm.nih.gov/pubmed/37047302
http://dx.doi.org/10.3390/ijms24076331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094578/
https://www.ncbi.nlm.nih.gov/pubmed/37047302
http://dx.doi.org/10.3390/ijms24076331

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