Docking and Selectivity Studies of Covalently Bound Janus Kinase 3 Inhibitors

The Janus kinases (JAKs) are a family of non-receptor cytosolic protein kinases critical for immune signaling. Many covalently bound ligands of JAK3 inhibitors have been reported. To help design selective JAK inhibitors, in this paper, we used five model proteins to study the subtype selectivity of...

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Detalles Bibliográficos
Autores principales: Zhong, Haizhen A., Almahmoud, Suliman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094608/
https://www.ncbi.nlm.nih.gov/pubmed/37047004
http://dx.doi.org/10.3390/ijms24076023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094608/
https://www.ncbi.nlm.nih.gov/pubmed/37047004
http://dx.doi.org/10.3390/ijms24076023

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