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Docking and Selectivity Studies of Covalently Bound Janus Kinase 3 Inhibitors
The Janus kinases (JAKs) are a family of non-receptor cytosolic protein kinases critical for immune signaling. Many covalently bound ligands of JAK3 inhibitors have been reported. To help design selective JAK inhibitors, in this paper, we used five model proteins to study the subtype selectivity of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094608/ https://www.ncbi.nlm.nih.gov/pubmed/37047004 http://dx.doi.org/10.3390/ijms24076023 |