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CA-IX-Expressing Small Extracellular Vesicles (sEVs) Are Released by Melanoma Cells under Hypoxia and in the Blood of Advanced Melanoma Patients

Cutaneous melanoma is a highly aggressive skin cancer, with poor prognosis. The tumor microenvironment is characterized by areas of hypoxia. Carbonic anhydrase IX (CA-IX) is a marker of tumor hypoxia and its expression is regulated by hypoxia-inducible factor-1 (HIF-1). CA-IX has been found to be hi...

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Detalles Bibliográficos
Autores principales: Venturella, Marta, Falsini, Alessandro, Coppola, Federica, Giuntini, Gaia, Carraro, Fabio, Zocco, Davide, Chiesi, Antonio, Naldini, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094632/
https://www.ncbi.nlm.nih.gov/pubmed/37047096
http://dx.doi.org/10.3390/ijms24076122