Effect of Single-Residue Mutations on CTCF Binding to DNA: Insights from Molecular Dynamics Simulations

In humans and other eukaryotes, DNA is condensed into chromatin fibers that are further wound into chromosomes. This organization allows regulatory elements in the genome, often distant from each other in the linear DNA, to interact and facilitate gene expression through regions known as topological...

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Detalles Bibliográficos
Autores principales: Mao, Albert, Chen, Carrie, Portillo-Ledesma, Stephanie, Schlick, Tamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094706/
https://www.ncbi.nlm.nih.gov/pubmed/37047368
http://dx.doi.org/10.3390/ijms24076395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094706/
https://www.ncbi.nlm.nih.gov/pubmed/37047368
http://dx.doi.org/10.3390/ijms24076395

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