Ethacrynic Acid: A Promising Candidate for Drug Repurposing as an Anticancer Agent

Ethacrynic acid (ECA) is a diuretic that inhibits Na-K-2Cl cotransporter (NKCC2) present in the thick ascending loop of Henle and muculo dens and is clinically used for the treatment of edema caused by excessive body fluid. However, its clinical use is limited due to its low bioavailability and side...

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Detalles Bibliográficos
Autores principales: Yu, Lu, Lee, Ho, Rho, Seung Bae, Park, Mi Kyung, Lee, Chang Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094867/
https://www.ncbi.nlm.nih.gov/pubmed/37047688
http://dx.doi.org/10.3390/ijms24076712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094867/
https://www.ncbi.nlm.nih.gov/pubmed/37047688
http://dx.doi.org/10.3390/ijms24076712

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