Cargando…
Up-Regulation of microRNA-424 Causes an Imbalance in AKT Phosphorylation and Impairs Enteric Neural Crest Cell Migration in Hirschsprung Disease
Insights into the role of microRNAs (miRNAs) in disease pathogenesis have made them attractive therapeutic targets, and numerous miRNAs have been functionally linked to Hirschsprung disease (HSCR), a life-threatening genetic disorder due to defective migration, proliferation, and colonization of ent...
Autores principales: | Xu, Ze, Yan, Yingnan, Gu, Beilin, Cai, Wei, Wang, Yang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094892/ https://www.ncbi.nlm.nih.gov/pubmed/37047673 http://dx.doi.org/10.3390/ijms24076700 |
Ejemplares similares
-
Transcriptomics of Hirschsprung disease patient-derived enteric neural crest cells reveals a role for oxidative phosphorylation
por: Li, Zhixin, et al.
Publicado: (2023) -
Questioning the failure of neural crest cell migration theory in Hirschsprung’s disease: A case report and literature review
por: Almumtin, Ahmed
Publicado: (2021) -
Impaired Cellular Immunity in the Murine Neural Crest Conditional Deletion of Endothelin Receptor-B Model of Hirschsprung’s Disease
por: Gosain, Ankush, et al.
Publicado: (2015) -
Mesenteric Neural Crest Cells Are the Embryological Basis of Skip Segment Hirschsprung’s Disease
por: Yu, Qi, et al.
Publicado: (2020) -
How Tissue Mechanical Properties Affect Enteric Neural Crest Cell Migration
por: Chevalier, N.R., et al.
Publicado: (2016)