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Atorvastatin Can Modulate DNA Damage Repair in Endothelial Cells Exposed to Mitomycin C

HMG-CoA reductase inhibitors (statins) are widely used in the therapy of atherosclerosis and have a number of pleiotropic effects, including DNA repair regulation. We studied the cytogenetic damage and the expression of DNA repair genes (DDB1, ERCC4, and ERCC5) in human coronary artery (HCAEC) and i...

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Detalles Bibliográficos
Autores principales: Sinitsky, Maxim, Asanov, Maxim, Sinitskaya, Anna, Shishkova, Daria, Khutornaya, Maria, Minina, Varvara, Ponasenko, Anastasia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094919/
https://www.ncbi.nlm.nih.gov/pubmed/37047754
http://dx.doi.org/10.3390/ijms24076783