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Overexpression of salusin-α upregulates AdipoR2 and activates the PPARα/ApoA5/SREBP-1c pathway to inhibit lipid synthesis in HepG2 cells

Salusin-α and adiponectin, are vasoactive peptides with numerous similar biological effects related to lipid metabolism. Adiponectin has been shown to reduce fatty acid oxidation and to inhibit lipid synthesis of liver cells through its receptor, adiponectin receptor 2 (AdipoR2), but whether salusin...

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Detalles Bibliográficos
Autores principales: Zhang, Huan, Yang, Chao, Wang, Songjiao, Xu, Aohong, Zhang, Qian, Duan, Xiuqun, Gong, Guofu, Wang, Yuxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094946/
https://www.ncbi.nlm.nih.gov/pubmed/37026514
http://dx.doi.org/10.3892/ijmm.2023.5244