NAGS, CPS1, and SLC25A13 (Citrin) at the Crossroads of Arginine and Pyrimidines Metabolism in Tumor Cells

Urea cycle enzymes and transporters collectively convert ammonia into urea in the liver. Aberrant overexpression of carbamylphosphate synthetase 1 (CPS1) and SLC25A13 (citrin) genes has been associated with faster proliferation of tumor cells due to metabolic reprogramming that increases the activit...

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Detalles Bibliográficos
Autores principales: Owusu-Ansah, Melissa, Guptan, Nikita, Alindogan, Dylon, Morizono, Michio, Caldovic, Ljubica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094985/
https://www.ncbi.nlm.nih.gov/pubmed/37047726
http://dx.doi.org/10.3390/ijms24076754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094985/
https://www.ncbi.nlm.nih.gov/pubmed/37047726
http://dx.doi.org/10.3390/ijms24076754

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