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NAGS, CPS1, and SLC25A13 (Citrin) at the Crossroads of Arginine and Pyrimidines Metabolism in Tumor Cells
Urea cycle enzymes and transporters collectively convert ammonia into urea in the liver. Aberrant overexpression of carbamylphosphate synthetase 1 (CPS1) and SLC25A13 (citrin) genes has been associated with faster proliferation of tumor cells due to metabolic reprogramming that increases the activit...
Autores principales: | Owusu-Ansah, Melissa, Guptan, Nikita, Alindogan, Dylon, Morizono, Michio, Caldovic, Ljubica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094985/ https://www.ncbi.nlm.nih.gov/pubmed/37047726 http://dx.doi.org/10.3390/ijms24076754 |
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