The Geroprotective Drug Candidate CMS121 Alleviates Diabetes, Liver Inflammation, and Renal Damage in db/db Leptin Receptor Deficient Mice

db/db mice, which lack leptin receptors and exhibit hyperphagia, show disturbances in energy metabolism and are a model of obesity and type 2 diabetes. The geroneuroprotector drug candidate CMS121 has been shown to be effective in animal models of Alzheimer’s disease and aging through the modulation...

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Detalles Bibliográficos
Autores principales: Zahid, Saadia, Dafre, Alcir L., Currais, Antonio, Yu, Jingting, Schubert, David, Maher, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095029/
https://www.ncbi.nlm.nih.gov/pubmed/37047807
http://dx.doi.org/10.3390/ijms24076828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095029/
https://www.ncbi.nlm.nih.gov/pubmed/37047807
http://dx.doi.org/10.3390/ijms24076828

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