Sitagliptin Mitigates Diabetic Nephropathy in a Rat Model of Streptozotocin-Induced Type 2 Diabetes: Possible Role of PTP1B/JAK-STAT Pathway

Diabetic nephropathy (DN) is a microvascular complication of diabetes mellitus. This study examined the therapeutic effects of sitagliptin, a dipeptidyl peptidase inhibitor, on DN and explored the underlying mechanism. Male Wistar albino rats (n = 12) were intraperitoneally administered a single dos...

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Detalles Bibliográficos
Autores principales: AL-Qabbaa, Sarah M., Qaboli, Samaher I., Alshammari, Tahani K., Alamin, Maha A., Alrajeh, Haya M., Almuthnabi, Lama A., Alotaibi, Rana R., Alonazi, Asma S., Bin Dayel, Anfal F., Alrasheed, Nawal M., Alrasheed, Nouf M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095069/
https://www.ncbi.nlm.nih.gov/pubmed/37047505
http://dx.doi.org/10.3390/ijms24076532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095069/
https://www.ncbi.nlm.nih.gov/pubmed/37047505
http://dx.doi.org/10.3390/ijms24076532

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