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Sitagliptin Mitigates Diabetic Nephropathy in a Rat Model of Streptozotocin-Induced Type 2 Diabetes: Possible Role of PTP1B/JAK-STAT Pathway
Diabetic nephropathy (DN) is a microvascular complication of diabetes mellitus. This study examined the therapeutic effects of sitagliptin, a dipeptidyl peptidase inhibitor, on DN and explored the underlying mechanism. Male Wistar albino rats (n = 12) were intraperitoneally administered a single dos...
Autores principales: | AL-Qabbaa, Sarah M., Qaboli, Samaher I., Alshammari, Tahani K., Alamin, Maha A., Alrajeh, Haya M., Almuthnabi, Lama A., Alotaibi, Rana R., Alonazi, Asma S., Bin Dayel, Anfal F., Alrasheed, Nawal M., Alrasheed, Nouf M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095069/ https://www.ncbi.nlm.nih.gov/pubmed/37047505 http://dx.doi.org/10.3390/ijms24076532 |
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