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Tracking of activated cTfh cells following sequential influenza vaccinations reveals transcriptional profile of clonotypes driving a vaccine-induced immune response

INTRODUCTION: A vaccine against influenza is available seasonally but is not 100% effective. A predictor of successful seroconversion in adults is an increase in activated circulating T follicular helper (cTfh) cells after vaccination. However, the impact of repeated annual vaccinations on long-term...

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Detalles Bibliográficos
Autores principales: Currenti, Jennifer, Simmons, Joshua, Oakes, Jared, Gaudieri, Silvana, Warren, Christian M., Gangula, Rama, Alves, Eric, Ram, Ramesh, Leary, Shay, Armitage, Jesse D., Smith, Rita M., Chopra, Abha, Halasa, Natasha B., Pilkinton, Mark A., Kalams, Spyros A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095155/
https://www.ncbi.nlm.nih.gov/pubmed/37063867
http://dx.doi.org/10.3389/fimmu.2023.1133781