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Genetic Analysis of Multiple Primary Malignant Tumors in Women with Breast and Ovarian Cancer

Familial cancer syndromes, which are commonly caused by germline mutations in oncogenes and tumor suppressor genes, are generally considered to be the cause of primary multiple malignant neoplasias (PMMNs). Using targeted genomic sequencing, we screened for eight germline mutations: BRCA1 185delAG,...

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Detalles Bibliográficos
Autores principales: Savkova, Alina, Gulyaeva, Lyudmila, Gerasimov, Aleksey, Krasil’nikov, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095199/
https://www.ncbi.nlm.nih.gov/pubmed/37047678
http://dx.doi.org/10.3390/ijms24076705