Effects of Human LAV-BPIFB4 Gene Therapy on the Epigenetic Clock and Health of Aged Mice

The homozygous genotype of the Longevity-Associated Variant (LAV) in Bactericidal/Permeability-Increasing Fold-Containing Family B member 4 (BPIFB4) is enriched in long-living individuals of three independent populations and its genetic transfer in C57BL/6J mice showed a delay in frailty progression...

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Detalles Bibliográficos
Autores principales: Giuliani, Maria Elisa, Barbi, Veronica, Bigossi, Giorgia, Marcozzi, Serena, Giacconi, Robertina, Cardelli, Maurizio, Piacenza, Francesco, Orlando, Fiorenza, Ciaglia, Elena, Cattaneo, Monica, Mongelli, Alessia, Gaetano, Carlo, Provinciali, Mauro, Puca, Annibale Alessandro, Malavolta, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095240/
https://www.ncbi.nlm.nih.gov/pubmed/37047437
http://dx.doi.org/10.3390/ijms24076464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095240/
https://www.ncbi.nlm.nih.gov/pubmed/37047437
http://dx.doi.org/10.3390/ijms24076464

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