Delineation of G Protein-Coupled Receptor Kinase Phosphorylation Sites within the D(1) Dopamine Receptor and Their Roles in Modulating β-Arrestin Binding and Activation

The D(1) dopamine receptor (D1R) is a G protein-coupled receptor that signals through activating adenylyl cyclase and raising intracellular cAMP levels. When activated, the D1R also recruits the scaffolding protein β-arrestin, which promotes receptor desensitization and internalization, as well as a...

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Detalles Bibliográficos
Autores principales: Moritz, Amy E., Madaras, Nora S., Rankin, Michele L., Inbody, Laura R., Sibley, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095280/
https://www.ncbi.nlm.nih.gov/pubmed/37047571
http://dx.doi.org/10.3390/ijms24076599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095280/
https://www.ncbi.nlm.nih.gov/pubmed/37047571
http://dx.doi.org/10.3390/ijms24076599

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