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The Role of Tyr-His-Trp Triad and Water Molecule Near the N1-Atom of 2-Hydroperoxycoelenterazine in Bioluminescence of Hydromedusan Photoproteins: Structural and Mutagenesis Study

Hydromedusan photoproteins responsible for the bioluminescence of a variety of marine jellyfish and hydroids are a unique biochemical system recognized as a stable enzyme-substrate complex consisting of apoprotein and preoxygenated coelenterazine, which is tightly bound in the protein inner cavity....

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Detalles Bibliográficos
Autores principales: Natashin, Pavel V., Burakova, Ludmila P., Kovaleva, Margarita I., Shevtsov, Mikhail B., Dmitrieva, Daria A., Eremeeva, Elena V., Markova, Svetlana V., Mishin, Alexey V., Borshchevskiy, Valentin I., Vysotski, Eugene S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095345/
https://www.ncbi.nlm.nih.gov/pubmed/37047842
http://dx.doi.org/10.3390/ijms24076869