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The Signaling Pathway of the ADP Receptor P2Y(12) in the Immune System: Recent Discoveries and New Challenges

P2Y(12) is a G-protein-coupled receptor that is activated upon ADP binding. Considering its well-established role in platelet activation, blocking P2Y(12) has been used as a therapeutic strategy for antiplatelet aggregation in cardiovascular disease patients. However, receptor studies have shown tha...

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Detalles Bibliográficos
Autores principales: Entsie, Philomena, Kang, Ying, Amoafo, Emmanuel Boadi, Schöneberg, Torsten, Liverani, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095349/
https://www.ncbi.nlm.nih.gov/pubmed/37047682
http://dx.doi.org/10.3390/ijms24076709