Inhibition of Soluble Epoxide Hydrolase Activity by Components of Glycyrrhiza uralensis

Soluble epoxide hydrolase (sEH) is a target enzyme for the treatment of inflammation and cardiovascular disease. A Glycyrrhiza uralensis extract exhibited ~50% inhibition of sEH at 100 μg/mL, and column chromatography yielded compounds 1–11. Inhibitors 1, 4–6, 9, and 11 were non-competitive; inhibit...

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Detalles Bibliográficos
Autores principales: Kim, Jang Hoon, Huh, Yun-Chan, Hur, Mok, Park, Woo Tae, Moon, Youn-Ho, Kim, Tae Il, Kim, Yong Il, Kim, Seon Mi, Lee, Jeonghoon, Lee, Ik Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095357/
https://www.ncbi.nlm.nih.gov/pubmed/37047457
http://dx.doi.org/10.3390/ijms24076485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095357/
https://www.ncbi.nlm.nih.gov/pubmed/37047457
http://dx.doi.org/10.3390/ijms24076485

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