Aβ Chronic Exposure Promotes an Activation State of Microglia through Endocannabinoid Signalling Imbalance

Dysfunctional phenotype of microglia, the primary brain immune cells, may aggravate Alzheimer’s disease (AD) pathogenesis by releasing proinflammatory factors, such as nitric oxide (NO). The endocannabinoids N-arachidonoylethanolamine (AEA) and 2-arachidonoylglycerol (2-AG) are bioactive lipids incr...

Descripción completa

Detalles Bibliográficos
Autores principales: Scipioni, Lucia, Tortolani, Daniel, Ciaramellano, Francesca, Fanti, Federico, Gazzi, Thais, Sergi, Manuel, Nazaré, Marc, Oddi, Sergio, Maccarrone, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095368/
https://www.ncbi.nlm.nih.gov/pubmed/37047663
http://dx.doi.org/10.3390/ijms24076684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095368/
https://www.ncbi.nlm.nih.gov/pubmed/37047663
http://dx.doi.org/10.3390/ijms24076684

Ejemplares similares