Electrophysiological Properties of Tetraploid Cardiomyocytes Derived from Murine Pluripotent Stem Cells Generated by Fusion of Adult Somatic Cells with Embryonic Stem Cells

Most cardiomyocytes (CMs) in the adult mammalian heart are either binucleated or contain a single polyploid nucleus. Recent studies have shown that polyploidy in CMs plays an important role as an adaptive response to physiological demands and environmental stress and correlates with poor cardiac reg...

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Detalles Bibliográficos
Autores principales: Xu, Guoxing, Fatima, Azra, Breitbach, Martin, Kuzmenkin, Alexey, Fügemann, Christopher J., Ivanyuk, Dina, Kim, Kee Pyo, Cantz, Tobias, Pfannkuche, Kurt, Schöler, Hans R., Fleischmann, Bernd K., Hescheler, Jürgen, Šarić, Tomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095437/
https://www.ncbi.nlm.nih.gov/pubmed/37047520
http://dx.doi.org/10.3390/ijms24076546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095437/
https://www.ncbi.nlm.nih.gov/pubmed/37047520
http://dx.doi.org/10.3390/ijms24076546

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