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Decreased SIRT1 Activity Is Involved in the Acute Injury Response of Chondrocytes to Ex Vivo Injurious Mechanical Overload

A better understanding of molecular events following cartilage injury is required to develop treatments that prevent or delay the onset of trauma-induced osteoarthritis. In this study, alterations to SIRT1 activity in bovine articular cartilage explants were evaluated in the 24 h following a mechani...

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Detalles Bibliográficos
Autores principales: Karnik, Sonali, Noori-Dokht, Hessam, Williams, Taylor, Joukar, Amin, Trippel, Stephen B., Sankar, Uma, Wagner, Diane R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095502/
https://www.ncbi.nlm.nih.gov/pubmed/37047494
http://dx.doi.org/10.3390/ijms24076521