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Decreased SIRT1 Activity Is Involved in the Acute Injury Response of Chondrocytes to Ex Vivo Injurious Mechanical Overload
A better understanding of molecular events following cartilage injury is required to develop treatments that prevent or delay the onset of trauma-induced osteoarthritis. In this study, alterations to SIRT1 activity in bovine articular cartilage explants were evaluated in the 24 h following a mechani...
Autores principales: | Karnik, Sonali, Noori-Dokht, Hessam, Williams, Taylor, Joukar, Amin, Trippel, Stephen B., Sankar, Uma, Wagner, Diane R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095502/ https://www.ncbi.nlm.nih.gov/pubmed/37047494 http://dx.doi.org/10.3390/ijms24076521 |
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