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Ablation of Death-Associated Protein Kinase 1 Changes the Transcriptomic Profile and Alters Neural-Related Pathways in the Brain

Death-associated protein kinase 1 (DAPK1), a Ca(2+)/calmodulin-dependent serine/threonine kinase, mediates various neuronal functions, including cell death. Abnormal upregulation of DAPK1 is observed in human patients with neurological diseases, such as Alzheimer’s disease (AD) and epilepsy. Ablatio...

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Detalles Bibliográficos
Autores principales: Li, Ruomeng, Zhi, Shuai, Lan, Guihua, Chen, Xiaotong, Zheng, Xiuzhi, Hu, Li, Wang, Long, Zhang, Tao, Lee, Tae Ho, Rao, Shitao, Chen, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095516/
https://www.ncbi.nlm.nih.gov/pubmed/37047515
http://dx.doi.org/10.3390/ijms24076542